Benefits of Myrcene Terpenes

Dominant in over 50% of cannabis strains, the “mother” of terpenes is myrcene, making up as much as 65% of the terpene profile in some strains, and it’s sometimes used in complementary and alternative medicine (CAM) for chemotherapy.  While directing cannabinoids as medicinal compounds, terpenes may promote relaxation, stress relief, energy and focus.  In fact, the ratios of cannabinoids and terpenes can ultimately predict the strain’s effects.  Many cannabis strains produce the effect of “couch lock,” due to the high levels of myrcene, but when it’s found elsewhere in nature, where THC is not a primary compound, it simply supports other properties.  It’s abundant in mangoes, bay leaves, basil, lemongrass, hops and thyme.

Myrcene is known for its earthy, musky aroma and has several potential benefits including:

• Sedative Effects: Myrcene is believed to have sedative properties, which can help with insomnia and anxiety.
• Pain Relief:  A review article in Pharmacological Reviews discussed the analgesic potential of terpenes, including myrcene, derived from Cannabis sativa. The review highlighted that myrcene, along with other terpenes, may contribute to the anti-inflammatory and antinociceptive (pain-relieving) effects of cannabis, making it useful for pain management.
• Anti-inflammatory: A study published in the International Journal of Molecular Sciences examined the role of myrcene in controlling chronic joint inflammation and pain in rats. The study found that myrcene reduced joint pain and inflammation via a cannabinoid receptor mechanism.  Because of this, myrcene can be beneficial for conditions like osteoarthritis.
• Antioxidant Properties: It can help protect cells from damage caused by free radicals.
• Anti-tumor Effects: Some studies suggest that myrcene may have anti-tumor properties, potentially aiding in cancer treatment.  Some terpenes can modulate different cellular signaling pathways involved in cancer cell proliferation, migration and death.

Along with other terpenes and cannabinoids, myrcene has shown particular potential in managing symptoms and side effects of chemotherapy.  When combined with cannabinoids like THC and CBD, can help alleviate symptoms such as pain, nausea, vomiting, loss of appetite, and sleep disturbances. This can significantly improve the quality of life for cancer patients.

Myrcene is particularly interesting when it interacts with other compounds and it plays a significant role in enhancing the overall experience of cannabis vaping:

• Entourage Effect: Myrcene works synergistically with cannabinoids like THC and CBD. This means that its presence can enhance the overall effect of these compounds, potentially making them more effective.
• Synergy with Other Terpenes: Myrcene can also work with other terpenes like pinene, limonene, and linalool to create unique therapeutic effects. For instance, a combination of myrcene and pinene might enhance focus and alertness, while myrcene and linalool might be more relaxing and sedative.
• Enhanced Absorption: Myrcene may increase the permeability of cell membranes, which can enhance the absorption of cannabinoids and other terpenes. This could make the effects of certain strains stronger or more pronounced.

These interactions are a big part of why different strains of cannabis can have such varied effects. It’s like having a different recipe for each strain, where the combination of ingredients (cannabinoids and terpenes) leads to a unique flavor and effect.

Uses in Products:

• Cannabis Products: Myrcene-rich strains are often sought after for their relaxing and sedative effects. Popular strains high in myrcene include sativa, indica and hybrid strains. Some popular strains include Super Silver Haze, White Widow, and OG Kush.

• Essential Oils: Myrcene is also a common component in essential oils used for aromatherapy. Its calming properties make it a favorite for stress relief and promoting sleep.

• Topicals: Some topical products may include myrcene for its anti-inflammatory and analgesic properties, providing localized relief for pain and inflammation.